In a study of 57 actual or impending
pathologic fractures of the humerus in 52 patients with inoperable
cancer treated between 1972 and 1982, we retrospectively reviewed the charts for analysis and comparison of the functional result and
pain relief afforded by the various treatments used. Function of the extremity and relief of
pain were each graded as excellent, good, fair, or poor using a modification of Perez's rating system. Seven
pathologic fractures were treated nonoperatively. These patients generally had only fair
pain relief and a poor functional result. Forty-six
pathologic fractures were treated with intramedullary fixation using a Rush rod (n = 16), a Küntscher rod (n = 29), or an Ender rod (n = 1); the Neer
endoprosthesis was used in four patients. Thirty-one patients received radiation to the humerus. There were seven operative complications, the most common (n = 3) being prominence of an intramedullary rod at the insertion site which required a second minor procedure for advancement of the rod. From this series, we conclude that any patient who has a
pathologic fracture or impending fracture of the humerus and a predicted survival of six weeks or more is likely to benefit from rigid internal fixation with an appropriately selected device, adjunctive use of
methylmethacrylate, and postoperative local irradiation
therapy as needed.