[Generalized lichen planus with erosive lesions of the penis, treated with thalidomide. Report of a case and review of the literature].

Abstract

A patient with generalized lichen planus with lesions in the infrequent localization like face, palms, soles and an extensive erosion of glans penis, is described in a 46 year old patient. He had received various treatment which include systemic steroids, without improvement. After treatment with thalidomide (initial doses 300 mg/day for 2 weeks and 200 mg/day for further 10 weeks) he presents resolution of his lesions and symptomatology. A review of lichen planus etiopathogenesis, making emphasis in the immunological hypothesis is made. As well as the different uses and action mechanism of thalidomide in various inflammatory dermatoses.

• Authors: R Pérez Alfonzo, E Weiss, J Piquero Martín, A Rondón Lugo
• Journal: Medicina cutanea ibero-latino-americana (Med Cutan Ibero Lat Am) Vol. 15 Issue 4 Pg. 321-6 ( 1987) ISSN: 0210-5187 [Print] Portugal
• Vernacular Title: Liquen plano generalizado con lesión erosiva del pene, tratado con talidomida. Reporte de un caso y revisión de la literatura.
• PMID: 3320627 (Publication Type: Case Reports, English Abstract, Journal Article, Review)

Topics

• Humans
• Lichen Planus (drug therapy, pathology)
• Male
• Middle Aged
• Penile Diseases (drug therapy, pathology)