Cellular composition of spleen and peritoneal exudate in mice after injection of cyclophosphamide-treated L 1210 leukemia cells.

Abstract

The composition of peritoneal exudate and spleen cells of CD2F1 mice after fourfold i.p. administration of L 1210 leukemia cells treated with cyclophosphamide (L 1210-CY cells) were examined. The number of cells in peritoneal cavity did not increase, however, the spleen weight rose after administration of L 1210-CY cells. The per cent of lymphocytes T was increased 2.5 times but the content of macrophages and lymphocytes B was normal in the peritoneal cavity after L 1210-CY cells injections. In the spleen an 1.4 times increase of the per cent of lymphocytes B, but normal level of macrophages and lymphocytes T were observed.

• Authors: T Skórski, M Kawalec, J Kawiak
• Journal: Folia histochemica et cytobiologica (Folia Histochem Cytobiol) Vol. 25 Issue 1 Pg. 23-7 ( 1987) ISSN: 0239-8508 [Print] Poland
• PMID: 3305097 (Publication Type: Journal Article)

Chemical References

• Cyclophosphamide

Topics

• Animals
• Ascitic Fluid (pathology)
• B-Lymphocytes (pathology)
• Cyclophosphamide (pharmacology)
• Histocytochemistry
• Immunoenzyme Techniques
• Leukemia L1210 (pathology)
• Mice
• Mice, Inbred BALB C
• Mice, Inbred DBA
• Neoplasm Transplantation
• Spleen (pathology)
• T-Lymphocytes (pathology)