The efficacy of single dose of pindolol in hypertension.

Abstract

The effect of pindolol was studied in 32 patients suffering from hypertension of WHO grad I or II. 25 of these patients respondered to pindolol administered three times daily, and were thereafter treated with a single 20-40 mg dose of pindolol. Normotension was achieved in 15 patients and a satisfactory result in five patients but three patients did not respond to the single dose and two had to interrupt their treatment because of side effects. The side effects were generally mild. As a significant observation NaCl retention was found. It may be due to the preceeding diuretic treatment in most patients, but nevertheless needs further investigations.

• Authors: S I Toivonen, S Mattila, S Tarpila, M Leirisalo
• Journal: Annals of clinical research (Ann Clin Res) Vol. 9 Issue 2 Pg. 93-6 (Apr 1977) ISSN: 0003-4762 [Print] Finland
• PMID: 329744 (Publication Type: Clinical Trial, Journal Article)

Chemical References

• Pindolol

Topics

• Clinical Trials as Topic
• Drug Evaluation
• Humans
• Hypertension (drug therapy)
• Pindolol (administration & dosage, therapeutic use)