Abstract |
18 infants and children (1 week to 3 months of age) were treated with cefotaxime 200 mg/kg/day for Gram-negative enteric bacillary meningitis. 17 of these patients (94.4%) survived, with a complication rate of 23.5% (4/17 patients). The follow-up cerebrospinal fluid cultures at 24 hours were sterile in all patients. Cefotaxime was safe and effective in treating Gram-negative enteric bacillary meningitis in infants and children and should be considered as a potential drug of choice in Gram-negative neonatal meningitis due to susceptible organisms.
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Authors | R F Jacobs |
Journal | Drugs
(Drugs)
Vol. 35 Suppl 2
Pg. 185-9
( 1988)
ISSN: 0012-6667 [Print] New Zealand |
PMID | 3293975
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Cefotaxime
(adverse effects, therapeutic use)
- Enterobacter
(isolation & purification)
- Escherichia coli
(isolation & purification)
- Female
- Follow-Up Studies
- Gram-Negative Bacteria
(isolation & purification)
- Humans
- Infant
- Infant, Newborn
- Klebsiella pneumoniae
(isolation & purification)
- Male
- Meningitis
(drug therapy, microbiology)
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