Abstract |
Patients with advanced Hodgkin's disease not achieving a complete remission with initial MOPP therapy are significantly less responsive to adriamycin and nitrosourea-containing regimens than patients with relapsing disease following a complete remission with MOPP. Hodgkin's disease not responding completely to initial four- drug treatment represents resistant disease which, in most instances, may not be cured with existing alternative chemotherapy. These patients should receive innovative treatment.
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Authors | M Coleman, R J Friedlander Jr |
Journal | Cancer investigation
(Cancer Invest)
Vol. 6
Issue 2
Pg. 237-9
( 1988)
ISSN: 0735-7907 [Print] England |
PMID | 3288299
(Publication Type: Journal Article, Review)
|
Chemical References |
- Procarbazine
- Mechlorethamine
- Vincristine
- Prednisone
|
Topics |
- Antineoplastic Combined Chemotherapy Protocols
(therapeutic use)
- Drug Administration Schedule
- Drug Resistance
- Hodgkin Disease
(drug therapy)
- Humans
- Mechlorethamine
(administration & dosage)
- Prednisone
(administration & dosage)
- Procarbazine
(administration & dosage)
- Recurrence
- Remission Induction
- Vincristine
(administration & dosage)
|