Neostigmine in postoperative intestinal paralysis. A double-blind, clinical, controlled trial.

Abstract

The effect of neostigmine on postoperative intestinal paralysis in 90 patients was investigated in a controlled study. Neostigmine, 0.5 mg, was administered intramuscularly every third hour on the third day after laparotomy, either until passage of flatus or stools was observed, or until a total of three injections were given. No difference between treated and untreated patients was found, and it is suggested that neostigmine is of little or no value in postoperative intestinal paralysis.

• Authors: T Myrhöj, O Olsen, B Wengel
• Journal: Diseases of the colon and rectum (Dis Colon Rectum) Vol. 31 Issue 5 Pg. 378-9 (May 1988) ISSN: 0012-3706 [Print] United States
• PMID: 3284726 (Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article, Randomized Controlled Trial)

Chemical References

• Neostigmine

Topics

• Clinical Trials as Topic
• Double-Blind Method
• Humans
• Intestinal Pseudo-Obstruction (drug therapy, etiology)
• Neostigmine (therapeutic use)
• Postoperative Complications (drug therapy)
• Random Allocation