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Gene sequences coding for S-adenosylmethionine decarboxylase are present on human chromosome 6 and the X and are not amplified in colon neoplasia.

Abstract
Sequences for human S-adenosylmethionine decarboxylase, an enzyme involved in polyamine biosynthesis, which is elevated in tumors, have been localized on chromosome 6 and the X.
AuthorsD M Radford, R Eddy, L Haley, W M Henry, A E Pegg, A Pajunen, T B Shows
JournalCytogenetics and cell genetics (Cytogenet Cell Genet) Vol. 49 Issue 4 Pg. 285-8 ( 1988) ISSN: 0301-0171 [Print] Switzerland
PMID3266848 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • DNA Probes
  • CTGCAG-specific type II deoxyribonucleases
  • Deoxyribonucleases, Type II Site-Specific
  • Carboxy-Lyases
  • Adenosylmethionine Decarboxylase
Topics
  • Adenosylmethionine Decarboxylase (genetics)
  • Animals
  • Carboxy-Lyases (genetics)
  • Chromosome Mapping
  • Chromosomes, Human, Pair 6
  • Colonic Neoplasms (enzymology, genetics)
  • Colonic Polyps (enzymology, genetics)
  • DNA Probes
  • Deoxyribonucleases, Type II Site-Specific
  • Gene Amplification
  • Humans
  • Hybrid Cells
  • Mice
  • Nucleic Acid Hybridization
  • Polymorphism, Genetic
  • X Chromosome

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