[Effects of T-activin in viral myocarditis in animal experiments].

Abstract

The efficacy of immunomodulating agent T-activin has been studied in adult BALB/C mice infected with Coxsackie B1 virus. Optical, electron microscopic and immunological tests have shown that T-activin protects myocardium and modulates immune disorders in mice with viral myocarditis.

• Authors: N N Kipshidze, M M Dzhaparidze, R V Bulusashvili, A V Khuchua, N A Zbiadadze
• Journal: Biulleten' eksperimental'noi biologii i meditsiny (Biull Eksp Biol Med) Vol. 105 Issue 6 Pg. 705-7 (Jun 1988) ISSN: 0365-9615 [Print] Russia (Federation)
• Vernacular Title: Vliianie T-aktivina na virusnyĭ miokardit v éksperimente.
• PMID: 3260519 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Adjuvants, Immunologic
• Peptides
• Thymus Extracts
• T-activin

Topics

• Adjuvants, Immunologic (therapeutic use)
• Animals
• Coxsackievirus Infections (drug therapy, immunology, pathology)
• Female
• Male
• Mice
• Mice, Inbred BALB C
• Myocarditis (drug therapy, immunology, pathology)
• Myocardium (pathology)
• Peptides (administration & dosage, therapeutic use)
• Rosette Formation
• T-Lymphocytes (immunology)
• Thymus Extracts (administration & dosage, therapeutic use)
• Time Factors