Abstract |
Immunocytochemical characterization of choroid plexus neoplasms was performed in seven cases, five being of benign choroid plexus papilloma ( CPP) and the other two of malignant choroid plexus papilloma ( choroid plexus carcinoma CPC). Immunohistochemical examination was performed with antibodies to glial fibrillary acidic protein (GFAP), S-100 protein, prealbumin, carcinoembryonic antigen (CEA), epithelial membrane antigen (EMA), and gamma-enolase. All of the five CPPs were positive for GFAP, S-100, prealbumin, and gamma-enolase; and four of them were positive for EMA. None of the CPPs was positive for CEA. Both of the two cases of CPC were positive for gamma-enolase, and one was positive for GFAP, S-100, EMA, and CEA. No CPC showed positivity for prealbumin. This report is the first to describe the usefulness of prealbumin reactivity for histological diagnosis of choroid plexus papillomas.
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Authors | T Matsushima, T Inoue, I Takeshita, M Fukui, T Iwaki, T Kitamoto |
Journal | Neurosurgery
(Neurosurgery)
Vol. 23
Issue 3
Pg. 384-9
(Sep 1988)
ISSN: 0148-396X [Print] United States |
PMID | 3226520
(Publication Type: Journal Article)
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Chemical References |
- Glial Fibrillary Acidic Protein
- Prealbumin
- S100 Proteins
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Topics |
- Adolescent
- Adult
- Aged
- Cerebral Ventricle Neoplasms
(metabolism, pathology)
- Child, Preschool
- Female
- Glial Fibrillary Acidic Protein
(metabolism)
- Humans
- Immunohistochemistry
- Infant
- Male
- Middle Aged
- Papilloma
(metabolism, pathology)
- Prealbumin
(metabolism)
- S100 Proteins
(metabolism)
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