Abstract |
Eighty four very low birthweight babies (considered high risk for developing necrotising enterocolitis) were given vancomycin orally for 48 hours before introduction of oral feeds; one developed necrotising enterocolitis. One hundred and twenty very low birthweight babies (not considered such high risk) were fed without first receiving vancomycin; 17 developed necrotising enterocolitis. Although this was not a randomised control trial, results indicate a role for vancomycin in prophylaxis of necrotising enterocolitis.
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Authors | P C Ng, P R Dear, D F Thomas |
Journal | Archives of disease in childhood
(Arch Dis Child)
Vol. 63
Issue 11
Pg. 1390-3
(Nov 1988)
ISSN: 1468-2044 [Electronic] England |
PMID | 3202650
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Administration, Oral
- Enterocolitis, Pseudomembranous
(prevention & control)
- Humans
- Infant, Low Birth Weight
- Infant, Newborn
- Infant, Premature, Diseases
(prevention & control)
- Vancomycin
(administration & dosage, therapeutic use)
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