Association of splenoma, peliosis and lipid histiocytosis in spleen or accessory spleen removed in 2 patients with chronic idiopathic thrombocytopenic purpura after long term treatment with steroids.

Abstract

In 2 patients with a long lasting cortico-dependent chronic idiopathic thrombocytopenic purpura, splenectomy in one and ablation of an accessory spleen in the other, disclosed a complex association of splenoma, peliosis and lipidosis of the spleen, with a secondary sea blue histiocytosis in one case. The relation of this curious association with thrombocytopenia and with the long treatment with corticosteroids is discussed, with a review of the literature.

• Authors: J Diebold, J Audouin
• Journal: Pathology, research and practice (Pathol Res Pract) Vol. 183 Issue 4 Pg. 446-52 (Aug 1988) ISSN: 0344-0338 [Print] Germany
• PMID: 3186545 (Publication Type: Case Reports, Journal Article)

Chemical References

• Adrenal Cortex Hormones

Topics

• Adrenal Cortex Hormones (therapeutic use)
• Aged
• Aged, 80 and over
• Female
• Humans
• Lymphatic Diseases (pathology)
• Middle Aged
• Purpura, Thrombocytopenic (drug therapy, pathology, surgery)
• Splenectomy
• Splenic Neoplasms (pathology)