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The effect of truncal vagotomy on the bicarbonate-ion secretion of the stomach in rat.

Abstract
The effect of truncal vagotomy on the gastric bicarbonate-ion, H-ion and chloride-ion secretions of the rat was studied experimentally. In the first half hour after truncal vagotomy, besides the known decrease of the H-ion, also the bicarbonate-ion and chloride-ion secretions were found reduced. The decrease in bicarbonate ion secretion was smaller as compared to the H-ion secretion. After two hours, there was no difference in bicarbonate-ion and chloride-ion secretions as compared to the controls and to the vagotomized groups. According to their results, following truncal vagotomy applied in the surgical management of ulcer, the bicarbonate-ion secretion of the stomach decreases immediately after operation. This decrease is, however, only transitory the bicarbonate-ion secretion becoming normal within a short time.
AuthorsS Dubecz Jr, D Szombath, J Sándor, T Gáti
JournalActa chirurgica Hungarica (Acta Chir Hung) Vol. 29 Issue 2 Pg. 131-6 ( 1988) ISSN: 0231-4614 [Print] Hungary
PMID3176787 (Publication Type: Journal Article)
Chemical References
  • Bicarbonates
Topics
  • Animals
  • Bicarbonates (metabolism)
  • Gastric Acidity Determination
  • Gastric Mucosa (metabolism)
  • Rats
  • Rats, Inbred Strains
  • Stomach (innervation)
  • Vagotomy, Truncal

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