Cytochemical detection of estrogen receptors in mammary tumours.

Abstract

The technical details of a cytochemical method for estrogen receptor identification in mammary tumours are presented and applied in 19 carcinomas and six adenofibromas. A fluorescent estradiol conjugate was used as receptor tracer. From the 19 mammary carcinomas, six were interpreted as estrogen receptor-negative (ER-), two were strongly receptor-positive (ER++) and eleven were moderately estrogen receptor-positive (ER+), having cells with a heterogeneous content of estrogen receptors. In fibroadenomas, the proliferating epithelia were moderately estrogen-receptor positive.

• Authors: V Gădăleanu, T H Gavrilescu
• Journal: Morphologie et embryologie (Morphol Embryol (Bucur)) 1985 Jan-Mar Vol. 31 Issue 1 Pg. 31-4 ISSN: 0377-5038 [Print] Romania
• PMID: 3157051 (Publication Type: Journal Article)

Chemical References

• Receptors, Estrogen

Topics

• Adenofibroma (metabolism)
• Breast Neoplasms (metabolism)
• Carcinoma (metabolism)
• Female
• Histocytochemistry
• Humans
• Microscopy, Fluorescence
• Receptors, Estrogen (metabolism)