Use of hyperthermia and radiotherapy in treatment of a large mast cell sarcoma in a dog.

Abstract

A large infiltrating mast cell sarcoma in a dog, which had been refractory before surgical excision, was controlled 2 months after completion of a combined radiotherapy and hyperthermia regimen. Treatment resulted in rapid tumor necrosis and resultant ulceration of adjacent skin. Ulceration was transient, resolving concurrently with tumor control. Radiation was administered as 3.5-Gy fractions 3 times/week, resulting in a total dose of 45.5 Gy in 13 treatments. Hyperthermia (44 C for 30 minutes) was given 4 to 5 hours after radiotherapy, once a week during the first 3 weeks of treatment.

• Authors: R A Legorreta, D L Denman, M C Kelley, G C Lewis Jr
• Journal: Journal of the American Veterinary Medical Association (J Am Vet Med Assoc) Vol. 193 Issue 12 Pg. 1545-8 (Dec 15 1988) ISSN: 0003-1488 [Print] United States
• PMID: 3145930 (Publication Type: Case Reports, Journal Article, Research Support, U.S. Gov't, P.H.S.)

Topics

• Animals
• Combined Modality Therapy
• Dog Diseases (radiotherapy, therapy)
• Dogs
• Extremities
• Female
• Hyperthermia, Induced (veterinary)
• Mast-Cell Sarcoma (radiotherapy, therapy, veterinary)
• Skin Neoplasms (radiotherapy, therapy, veterinary)