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Hypertrophy of the inferior olivary nucleus. A clinico-pathological observation.

Abstract
The clinico-pathological findings in a 61-year-old man, who suffered from branchial and skeletal myoclonus, appearing six months after a brainstem infarction are reported. Of all the drugs which are usually thought to be effective in the treatment of myoclonus, only valproic acid brought some relief. The necropsy revealed bilateral hypertrophy of the olives, together with bilateral pontine tegmental and rubral infarctions, without involvement of the olivary pathway.
AuthorsJ De Bleecker, J De Reuck, W Van Landegem, G Meersman
JournalActa neurologica Belgica (Acta Neurol Belg) 1988 Aug-Oct Vol. 88 Issue 4 Pg. 221-8 ISSN: 0300-9009 [Print] Italy
PMID3144824 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Valproic Acid
Topics
  • Brain Stem (blood supply)
  • Cerebral Infarction (complications, pathology)
  • Humans
  • Hypertrophy
  • Male
  • Mesencephalon
  • Middle Aged
  • Myoclonus (drug therapy, etiology)
  • Olivary Nucleus (pathology)
  • Pons
  • Valproic Acid (therapeutic use)

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