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[A case of recurrent sigmoid colon cancer successfully treated with 5-FU and UFT].

Abstract
A 57-year-old female patient with recurrent sigmoid colon cancer was successfully treated with 5-FU and UFT for 8 years. The patient, with cancer recurrence in the para-aortic lymph nodes, which were palpated in the abdomen, was given oral 5-FU at a daily dose of 200 mg. During the second week of administration, the mass showed a remarkable decrease in size, and complete disappearance was achieved within one month. However, 5 years and 2 months after discontinuation of 5-FU administration, recurrence in the supra-clavicular lymph nodes and para-aortic lymph nodes was recognized. After administration of UFT at a daily dose of 600 mg, complete disappearance of para-aortic lymph node recurrence was observed. At present, the patient is under observation as an outpatient at our hospital. This case suggests the effectiveness of 5-FU and UFT for lymph node metastases of sigmoid colon cancer.
AuthorsE Otsuji, T Yamaguchi, T Yamane, Y Fujita, T Takahashi, B Nishioka
JournalGan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 15 Issue 3 Pg. 523-6 (Mar 1988) ISSN: 0385-0684 [Print] Japan
PMID3126710 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Tegafur
  • Uracil
  • Fluorouracil
Topics
  • Adenocarcinoma (drug therapy, pathology)
  • Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
  • Female
  • Fluorouracil (administration & dosage)
  • Humans
  • Lymphatic Metastasis
  • Middle Aged
  • Sigmoid Neoplasms (drug therapy, pathology)
  • Tegafur (administration & dosage)
  • Uracil (administration & dosage)

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