Abstract |
A 57-year-old female patient with recurrent sigmoid colon cancer was successfully treated with 5-FU and UFT for 8 years. The patient, with cancer recurrence in the para-aortic lymph nodes, which were palpated in the abdomen, was given oral 5-FU at a daily dose of 200 mg. During the second week of administration, the mass showed a remarkable decrease in size, and complete disappearance was achieved within one month. However, 5 years and 2 months after discontinuation of 5-FU administration, recurrence in the supra-clavicular lymph nodes and para-aortic lymph nodes was recognized. After administration of UFT at a daily dose of 600 mg, complete disappearance of para-aortic lymph node recurrence was observed. At present, the patient is under observation as an outpatient at our hospital. This case suggests the effectiveness of 5-FU and UFT for lymph node metastases of sigmoid colon cancer.
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Authors | E Otsuji, T Yamaguchi, T Yamane, Y Fujita, T Takahashi, B Nishioka |
Journal | Gan to kagaku ryoho. Cancer & chemotherapy
(Gan To Kagaku Ryoho)
Vol. 15
Issue 3
Pg. 523-6
(Mar 1988)
ISSN: 0385-0684 [Print] Japan |
PMID | 3126710
(Publication Type: Case Reports, English Abstract, Journal Article)
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Chemical References |
- Tegafur
- Uracil
- Fluorouracil
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Topics |
- Adenocarcinoma
(drug therapy, pathology)
- Antineoplastic Combined Chemotherapy Protocols
(therapeutic use)
- Female
- Fluorouracil
(administration & dosage)
- Humans
- Lymphatic Metastasis
- Middle Aged
- Sigmoid Neoplasms
(drug therapy, pathology)
- Tegafur
(administration & dosage)
- Uracil
(administration & dosage)
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