Euthyroid hyperthyroxinemia and inappropriate secretion of thyrotropin. Recognition and diagnosis.

Abstract

Various disease states associated with euthyroid hyperthyroxinemia and inappropriate thyrotropin secretion are becoming increasingly recognized. These diagnoses were established in six (11%) of 57 patients referred for evaluation of elevated free thyroxine index over an 11-month period. Failure to separate these entities from primary thyrotoxicosis may result in unnecessary thyroid ablative therapy and subsequent clinical confusion. Several illustrative patient summaries are presented to outline an approach to this clinical challenge.

• Authors: J A Jackson, C A Verdonk, A M Spiekerman
• Journal: Archives of internal medicine (Arch Intern Med) Vol. 147 Issue 7 Pg. 1311-3 (Jul 1987) ISSN: 0003-9926 [Print] United States
• PMID: 3111399 (Publication Type: Case Reports, Journal Article)

Chemical References

• Thyrotropin-Releasing Hormone
• Thyrotropin

Topics

• Adolescent
• Adult
• Aged
• Diagnosis, Differential
• Female
• Goiter (diagnosis)
• Graves Disease (diagnosis)
• Humans
• Hyperthyroxinemia (diagnosis, physiopathology)
• Infant
• Male
• Middle Aged
• Thyroid Function Tests
• Thyroid Gland (physiopathology)
• Thyroidectomy
• Thyrotoxicosis (diagnosis)
• Thyrotropin (metabolism)
• Thyrotropin-Releasing Hormone (blood)