Abstract |
Chronic cerebrovascular disorders (CCVD), as defined by the 1980 Ad Hoc Committee in Paris, constitute both clinically and pathogenetically an extremely complex entity, characterized by a protean symptom pattern. The effects of a daily dose of 10 mg flunarizine orally on CCVD have been evaluated with a neuropsychological methodology during a three-month treatment period in a randomized double-blind study compared with a placebo. The results confirmed the effectiveness of the drug in the improvement of neurological, amnesic, attentive and behavioural symptoms, without evident side-effects even after a long-term treatment.
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Authors | A Agnoli, V Manna, N Martucci, M Fioravanti, F Ferromilone, A Cananzi, G D'Andrea, A De Rosa, R Vizioli, E Sinforiani |
Journal | International journal of clinical pharmacology research
(Int J Clin Pharmacol Res)
Vol. 8
Issue 3
Pg. 189-97
( 1988)
ISSN: 0251-1649 [Print] Switzerland |
PMID | 3042644
(Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)
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Chemical References |
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Topics |
- Adult
- Aged
- Cerebrovascular Disorders
(drug therapy)
- Clinical Trials as Topic
- Double-Blind Method
- Female
- Flunarizine
(adverse effects, therapeutic use)
- Humans
- Male
- Middle Aged
- Random Allocation
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