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Inhaler usability of a pressurized metered dose inhaler and a soft mist inhaler in patients with COPD: A simulated-use study.

Abstract
The objective of this study was to evaluate task performance and handling errors with soft mist inhalers (SMIs) or pressurized metered-dose inhalers (pMDIs) among patients with chronic obstructive pulmonary disease (COPD) experienced with, but not recently trained in, using these devices. This exploratory, noninterventional, simulated-use study (D5970R00004) assessed handling/usability of SMIs and pMDIs in inhaler-experienced patients with COPD (40-78 years; diagnosis ≥6 months). Patients received a device and instruction-for-use leaflet but no training and were recorded while performing tasks required for checking the device, priming, and dosing. Errors that could substantially affect the lung-delivered dose were considered critical. Sixteen of 61 patients (52% male) had used SMIs and 55 had used pMDIs. Thirty-one patients received an SMI and 30 a pMDI. Overall, 79% made ≥5 performance errors (SMI 94%; pMDI 63%) and 49% made ≥5 critical errors (SMI 68%; pMDI 30%). All patients made ≥1 error; three (all pMDI) made no critical errors. Regardless of the device used and previous inhaler experience, patient-centered training, education, and continuous retraining on correct inhaler use should be key aspects of routine patient care in COPD.
AuthorsBo Ding, Shahid Siddiqui, Michael DePietro, Gunilla Petersson, Ubaldo J Martin
JournalChronic respiratory disease (Chron Respir Dis) 2019 Jan-Dec Vol. 16 Pg. 1479972318787914 ISSN: 1479-9731 [Electronic] England
PMID30016880 (Publication Type: Journal Article, Multicenter Study)
Chemical References
  • Bronchodilator Agents
Topics
  • Administration, Inhalation
  • Adult
  • Aged
  • Aged, 80 and over
  • Bronchodilator Agents (administration & dosage)
  • Dose-Response Relationship, Drug
  • Equipment Design
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Metered Dose Inhalers (statistics & numerical data)
  • Middle Aged
  • Patient Compliance
  • Pulmonary Disease, Chronic Obstructive (drug therapy)
  • Retrospective Studies

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