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Potency and efficacy of inactivated bluetongue virus vaccines.

Abstract
Bluetongue virus (BTV) was chemically inactivated and was shown to elicit neutralizing antibodies in vaccinated rabbits and sheep. In sheep, the neutralizing antibody was shown to be protective by immunity challenge with virulent virus. These studies have shown the feasibility of safe and effective inactivated vaccines for bluetongue (BT) disease of sheep.
AuthorsD R Stevens, J Stott, B I Osburn, R Giles, G P Wiesehahn, T L Barber
JournalProgress in clinical and biological research (Prog Clin Biol Res) Vol. 178 Pg. 649-52 ( 1985) ISSN: 0361-7742 [Print] United States
PMID2989914 (Publication Type: Journal Article)
Chemical References
  • Antibodies, Viral
  • Viral Vaccines
Topics
  • Animals
  • Antibodies, Viral (biosynthesis)
  • Bluetongue (prevention & control)
  • Bluetongue virus (immunology)
  • Rabbits
  • Reoviridae (immunology)
  • Sheep (immunology)
  • Viral Vaccines (immunology)

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