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A trial of intranasal Atrovent versus placebo in the treatment of vasomotor rhinitis.

Abstract
Twenty-six patients with perennial rhinorrhea were treated by Atrovent, the anticholinergic agent, or placebo in a randomized double-blind crossover trial. The severity and duration of rhinorrhea were significantly reduced by Atrovent. Local side effects were more frequent with the active drug. These were reduced in a later open trial by a reduction in dosage.
AuthorsA Knight, F Kazim, V A Salvatori
JournalAnnals of allergy (Ann Allergy) Vol. 57 Issue 5 Pg. 348-54 (Nov 1986) ISSN: 0003-4738 [Print] United States
PMID2946252 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
Chemical References
  • Atropine Derivatives
  • Ipratropium
Topics
  • Administration, Intranasal
  • Adolescent
  • Adult
  • Atropine Derivatives (therapeutic use)
  • Clinical Trials as Topic
  • Double-Blind Method
  • Female
  • Humans
  • Ipratropium (administration & dosage, adverse effects, therapeutic use)
  • Male
  • Middle Aged
  • Random Allocation
  • Rhinitis, Vasomotor (drug therapy)

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