Abstract |
A total of 323 Escherichia coli strains from children with primary acute non-obstructive pyelonephritis (n = 144) or cystitis (n = 56) and from adults with acute non-obstructive pyelonephritis (n = 66) or cystitis (n = 57) were examined for presence of the aerobactin-mediated iron uptake system and expression of P-fimbriae. Overall, pyelonephritogenic Escherichia coli strains were significantly more often aerobactin-positive (72%) than cystitis strains (42%) (p less than 0.001). Seventy-three percent of the isolates from children with acute pyelonephritis were aerobactin-positive compared to 54% of the cystitis strains (p less than 0.05). Pyelonephritogenic Escherichia coli strains from adults were also significantly more often aerobactin-positive (70%) than cystitis strains (30%) (p less than 0.001). The cystitis strains from children were more often aerobactin-positive than cystitis strains from adult patients (p less than 0.05). There was a significant correlation between presence of the aerobactin-mediated iron uptake system and expression of P-fimbriae in all strains (p less than 0.001).
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Authors | S H Jacobson, M Hammarlind, K J Lidefeldt, E Osterberg, K Tullus, A Brauner |
Journal | European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
(Eur J Clin Microbiol Infect Dis)
Vol. 7
Issue 5
Pg. 630-4
(Oct 1988)
ISSN: 0934-9723 [Print] Germany |
PMID | 2904370
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Hydroxamic Acids
- Iron Chelating Agents
- aerobactin
- Iron
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Topics |
- Adolescent
- Adult
- Aged
- Child
- Child, Preschool
- Cystitis
(microbiology)
- Escherichia coli
(growth & development, metabolism, ultrastructure)
- Escherichia coli Infections
(microbiology)
- Female
- Fimbriae, Bacterial
(ultrastructure)
- Humans
- Hydroxamic Acids
(biosynthesis)
- Iron
(metabolism)
- Iron Chelating Agents
(metabolism)
- Middle Aged
- Pyelonephritis
(microbiology)
- Urinary Tract Infections
(microbiology)
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