Somatostatin does not reduce oesophageal variceal pressure in liver cirrhotics.

Abstract

Transmural oesophageal variceal pressure was determined by direct puncture of the varices in 27 patients with liver cirrhosis and oesophageal varices. Variceal pressure was not influenced three to six minutes after somatostatin bolus administration and slightly increased during somatostatin infusion. Thus, potential haemostatic benefits of somatostatin cannot be explained by pressure reductions in the varices.

• Authors: G Kleber, T Sauerbruch, G Fischer, G Paumgartner
• Journal: Gut (Gut) Vol. 29 Issue 2 Pg. 153-6 (Feb 1988) ISSN: 0017-5749 [Print] England
• PMID: 2894336 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Somatostatin

Topics

• Blood Pressure (drug effects)
• Esophageal and Gastric Varices (complications, drug therapy, physiopathology)
• Female
• Humans
• Liver Cirrhosis (complications)
• Liver Cirrhosis, Alcoholic (complications)
• Male
• Middle Aged
• Somatostatin (therapeutic use)