Pharmacotherapy of nasal disease.

Abstract

Rhinitis may be classified as infectious (purulent), seasonal allergic, perennial allergic, perennial nonallergic (vasomotor) and nasal polyps. Pharmacotherapy can be local or systemic. A variety of compounds are available, including alpha adrenergic agonists, mast cell stabilizing agents, Beta-2 agonists, antihistamines, cholinergic antagonists and corticosteroids. In terms of histamine receptors, H1 receptors predominate in the epithelium and glands but both H1 and H2 receptors are present in nasal blood vessels. Trigeminus-reflex mediated nasal secretions, can be treated by parasympatholytic drugs.

• Authors: N Mygind
• Journal: New England and regional allergy proceedings (N Engl Reg Allergy Proc) Vol. 6 Issue 3 Pg. 245-8 ( 1985) ISSN: 0742-2814 [Print] United States
• PMID: 2888012 (Publication Type: Journal Article)

Chemical References

• Adrenergic alpha-Agonists
• Histamine H1 Antagonists
• Parasympatholytics
• Vasoconstrictor Agents
• Vasodilator Agents

Topics

• Adrenergic alpha-Agonists (therapeutic use)
• Histamine H1 Antagonists (therapeutic use)
• Humans
• Mast Cells (drug effects)
• Nasal Polyps (drug therapy)
• Parasympatholytics (therapeutic use)
• Rhinitis (classification, drug therapy, etiology)
• Vasoconstrictor Agents (therapeutic use)
• Vasodilator Agents (therapeutic use)