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Efficacy and safety of two different dose levels of ganciclovir for the treatment of cytomegalovirus chorioretinitis in AIDS patients.

Abstract
The effect of different dosages of ganciclovir on proved cytomegalovirus chorioretinitis was tested in a randomized trial on 11 homosexual men with AIDS. The effect of 5 mg/kg/day was as good as 10 mg/kg/day. The lower dosage had less toxicity.
AuthorsJ Gaub, A G Poulsen, C Pedersen, S Tinning, K Højgaard, M H Thomson, V Faber, J O Nielsen
JournalScandinavian journal of infectious diseases (Scand J Infect Dis) Vol. 20 Issue 5 Pg. 479-82 ( 1988) ISSN: 0036-5548 [Print] England
PMID2851877 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)
Chemical References
  • Antiviral Agents
  • Ganciclovir
  • Acyclovir
Topics
  • Acquired Immunodeficiency Syndrome (complications)
  • Acyclovir (administration & dosage, analogs & derivatives, therapeutic use)
  • Adult
  • Antiviral Agents (administration & dosage, therapeutic use)
  • Chorioretinitis (drug therapy, etiology)
  • Clinical Trials as Topic
  • Cytomegalovirus Infections (drug therapy, etiology)
  • Ganciclovir
  • Humans
  • Male
  • Middle Aged
  • Random Allocation

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