Circulating plasma alpha-tocopherol following a single injection in a black rhinoceros (Diceros bicornis).

Abstract

Injectable all rac-alpha-tocopherol, at a dose of 12.4 IU/kg body mass, increased circulating levels of alpha-tocopherol in the black rhinoceros (Bicornis diceros) from 0.18 microgram/ml to 1.47 micrograms/ml within 2 hr. Although the plasma level peaked at Day one (13.07 micrograms/ml) and dropped rapidly, substantial residual effects were seen even 10 days (1.50 micrograms/ml) following a single injection. It appears that parenteral vitamin E administration may be suitable for therapeutic treatment of vitamin E deficiency in the black rhinoceros.

• Authors: E S Dierenfeld, S B Citino
• Journal: Journal of wildlife diseases (J Wildl Dis) Vol. 25 Issue 4 Pg. 647-8 (Oct 1989) ISSN: 0090-3558 [Print] United States
• PMID: 2810570 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Vitamin E

Topics

• Animals
• Female
• Injections, Intramuscular (veterinary)
• Perissodactyla (blood, metabolism)
• Vitamin E (administration & dosage, blood, pharmacokinetics)