[The pentosephosphate pathway of carbohydrate metabolism in evaluating the pharmacologic correction of immuno-inflammatory processes in systemic connective tissue diseases].

Abstract

Treatment with roxicam, rengasil and flugalin tended significantly to normalize the activity of enzymes of carbohydrate metabolism pentosophosphate pathway in the blood of patients with systemic lupus erythematosus and rheumatoid arthritis. The dynamics of the change in the activity of enzymes of pentose phosphate pathway in the blood of patients with systemic connective tissue diseases against the background of treatment with roxicam, rengasil and flugalin is the enzymological criterion in assessing efficacy of pharmacological correction of the inflammatory process in the diseases.

• Authors: V I Shishkin, G V Kudriavtseva, S A Makarov
• Journal: Farmakologiia i toksikologiia (Farmakol Toksikol) 1989 May-Jun Vol. 52 Issue 3 Pg. 73-7 ISSN: 0014-8318 [Print] Russia (Federation)
• Vernacular Title: Pentozofosfatnyĭ put' obmena uglevodov v otsenke farmakologicheskoĭ korrektsii immunovospalitel'nogo protsessa pri sistemnykh zabolevaniiakh soedinitel'noĭ tkani.
• PMID: 2792359 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Anti-Inflammatory Agents, Non-Steroidal
• Phenylpropionates
• Flurbiprofen
• pirprofen

Topics

• Adult
• Anti-Inflammatory Agents, Non-Steroidal (therapeutic use)
• Arthritis, Rheumatoid (drug therapy, immunology, metabolism)
• Carbohydrate Metabolism
• Female
• Flurbiprofen (therapeutic use)
• Humans
• Lupus Erythematosus, Systemic (drug therapy, immunology, metabolism)
• Male
• Middle Aged
• Pentose Phosphate Pathway
• Phenylpropionates (therapeutic use)