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Open trial of fluoxetine in obsessive-compulsive disorder.

Abstract
A 12-week open trial of fluoxetine in 61 obsessive-compulsive disorder patients significantly improved depressive and obsessive-compulsive symptoms. Baseline depression scores were not related to improvement on two obsessive-compulsive scales. The results reinforce the hypothesis of serotonergic abnormalities in obsessive-compulsive disorder.
AuthorsM A Jenike, L Buttolph, L Baer, J Ricciardi, A Holland
JournalThe American journal of psychiatry (Am J Psychiatry) Vol. 146 Issue 7 Pg. 909-11 (Jul 1989) ISSN: 0002-953X [Print] United States
PMID2787123 (Publication Type: Journal Article)
Chemical References
  • Fluoxetine
Topics
  • Adult
  • Depression (drug therapy)
  • Female
  • Fluoxetine (administration & dosage, therapeutic use)
  • Humans
  • Male
  • Obsessive-Compulsive Disorder (drug therapy)
  • Personality Tests

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