Abstract |
A 12-week open trial of fluoxetine in 61 obsessive-compulsive disorder patients significantly improved depressive and obsessive-compulsive symptoms. Baseline depression scores were not related to improvement on two obsessive-compulsive scales. The results reinforce the hypothesis of serotonergic abnormalities in obsessive-compulsive disorder.
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Authors | M A Jenike, L Buttolph, L Baer, J Ricciardi, A Holland |
Journal | The American journal of psychiatry
(Am J Psychiatry)
Vol. 146
Issue 7
Pg. 909-11
(Jul 1989)
ISSN: 0002-953X [Print] United States |
PMID | 2787123
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adult
- Depression
(drug therapy)
- Female
- Fluoxetine
(administration & dosage, therapeutic use)
- Humans
- Male
- Obsessive-Compulsive Disorder
(drug therapy)
- Personality Tests
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