[Efficacy of treating patients with disseminated forms of destructive pulmonary tuberculosis using chemical preparations and T-activin].

Abstract

The use of T-activin in combination with chemical drugs allowed to markedly increase efficacy of the treatment. As a result of the treatment significant improvement was found in 17 (41.5 per cent) out of 41 patients with marked disorders in cellular immunity and severe tuberculosis. At the same time in the patients treated with the chemotherapeutics alone the improvement was stated only in 18.5 per cent of the patients. T-Activin improved the indices of cellular immunity and eliminated imbalance in regulatory subpopulations of T-helper and T-suppressor cells.

• Authors: V I Chukanov, V Ia Gergert, I S Khomenko
• Journal: Problemy tuberkuleza (Probl Tuberk) Issue 6 Pg. 30-3 ( 1989) ISSN: 0032-9533 [Print] Russia (Federation)
• Vernacular Title: Effektivnost' lecheniia khimiopreparatami i T-aktivinom bol'nykh s rasprostranennymi formami destruktivnogo tuberkuleza legkikh.
• PMID: 2771908 (Publication Type: English Abstract, Journal Article)

Chemical References

• Adjuvants, Immunologic
• Antitubercular Agents
• Peptides
• Thymus Extracts
• T-activin

Topics

• Adjuvants, Immunologic (therapeutic use)
• Antitubercular Agents (therapeutic use)
• Humans
• Peptides (therapeutic use)
• Thymus Extracts (therapeutic use)
• Tuberculosis, Pulmonary (drug therapy, immunology)