A case of Vogt-Koyanagi-Harada syndrome in a patient affected by Hodgkin's disease.

Abstract

The Vogt-Koyanagi-Harada (VKH) syndrome, a disease of unknown origin, characterized by inflammation of the uveal tract, retina and meninges, was observed in a patient with Hodgkin's disease (HD) who had been treated with chemotherapy and radiotherapy. Ten years later the patient developed a cluster of neurological symptoms and signs (fever, pain, bilateral hypoacousia, dizziness, uveitis and psychiatric disorder) which were initially interpreted as a relapse of HD. The diagnosis of VKH syndrome was thereafter suspected from the clinical findings, response to therapy and further evolution. During the follow-up (14 months) the patient showed a varying course; hypoacousia remained unaltered while uveitis recurred and only a partial improvement was obtained by immunosuppressive therapy.

• Authors: D Cipriani, G Landonio, C Canepari
• Journal: Journal of neurology (J Neurol) Vol. 236 Issue 5 Pg. 303-4 (Jul 1989) ISSN: 0340-5354 [Print] Germany
• PMID: 2760648 (Publication Type: Case Reports, Journal Article)

Topics

• Female
• Hodgkin Disease (complications)
• Humans
• Middle Aged
• Uveitis (complications)
• Uveomeningoencephalitic Syndrome (complications)