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Probable hypersensitivity vasculitis in a dog.

Abstract
Allergy immunotherapy (hyposensitization) injections or ibuprofen were implicated as causes of hypersensitivity vasculitis in a dog suffering from probable food allergy. The vasculitis was associated with increased complement component, C3, and resulted in deep, ulcerated draining nodules and plaques on the forelimbs, lateral aspects of the thorax, and thighs. Injections had been given as immunotherapy for suspected atopy. Vasculitis, associated with allergy immunotherapy and increased complement component, C3, as well as with nonsteroidal anti-inflammatory drugs, has been reported in human beings.
AuthorsM A Rachofsky, D K Chester, W K Read, J D Conroy
JournalJournal of the American Veterinary Medical Association (J Am Vet Med Assoc) Vol. 194 Issue 11 Pg. 1592-4 (Jun 01 1989) ISSN: 0003-1488 [Print] United States
PMID2753779 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Complement C3
  • Ibuprofen
Topics
  • Animals
  • Complement C3 (analysis)
  • Desensitization, Immunologic (adverse effects)
  • Dog Diseases (etiology, therapy)
  • Dogs
  • Food Hypersensitivity (therapy, veterinary)
  • Ibuprofen (adverse effects)
  • Male
  • Vasculitis, Leukocytoclastic, Cutaneous (etiology, veterinary)

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