[A successful case of cisplatin-treated bartholin gland carcinoma].

Abstract

A case of advanced cancer of the vulva that was treated by cisplatin with good result, is reported. This case was adenocarcinoma of Bartholin gland, and the clinical stage was third stage. The method of administration was intravenous injection of cisplatin (150 mg/body) in hypertonic saline (3%) for the decrease of nephrotoxicity. After administration (450 mg/body), the tumor markedly reduced. Additional operation, one course of CDDP and irradiation were carried out. After discharge, there has been no sign of recurrence for one year and five months. In this case, we used CDDP in hypertonic saline to decrease the nephrotoxicity. During these courses, the nephrotoxicity was moderate. This shows that patients can be treated by higher-doses of cisplatinum by this method.

• Authors: A Arakawa, Y Yasui, K Suzumori, K Suzumori, Y Yagami, T Nakamura
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 16 Issue 7 Pg. 2437-40 (Jul 1989) ISSN: 0385-0684 [Print] Japan
• PMID: 2751320 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Cisplatin

Topics

• Adenocarcinoma (drug therapy, radiotherapy)
• Adult
• Bartholin's Glands
• Cisplatin (administration & dosage, therapeutic use)
• Combined Modality Therapy
• Drug Administration Schedule
• Female
• Humans
• Injections, Intravenous
• Vulvar Neoplasms (drug therapy, radiotherapy)