[An experimental study of the pathogenetic mechanisms of uveitis following cataract extraction and implantation of an artificial lens].

Abstract

The paper analyses results after experimental investigations for detection of some mechanisms of postoperative anterior uveitis after lens extraction and implantation of intraocular lens. The methods used were preliminary sensitization of animals by the lens antigen and polymethyl methacrylate, blast transformation reaction, thermometric and biochemical investigations. It is stated that preliminary sensitization stimulates development of a more expressed postoperative inflammatory reaction producing increased sensitivity of animals to antigens. At this, the role of a sensitizing factor can be realized by the lens protein as well as by polymethyl methacrylate. Preliminary immunization of animals in the postoperative period is accompanied by the increase of temperature values and concentration of protein the aqueous humor.

• Authors: Z F Veselovskaia, O V Khaĭlova
• Journal: Oftalmologicheskii zhurnal (Oftalmol Zh) Issue 1 Pg. 41-4 ( 1989) ISSN: 0030-0675 [Print] Ukraine
• Vernacular Title: Eksperimental'noe issleovanie nekotorykh patogeneticheskikh mekhanizmov uveita posle ékstraktsii katarakty s implantatsieĭ iskustvennogo khrustalika.
• PMID: 2733971 (Publication Type: English Abstract, Journal Article)

Topics

• Animals
• Lenses, Intraocular (adverse effects)
• Rabbits
• Uveitis (etiology, immunology)