We report the results of a clinical study of the
male sterility in our institute during the past 55 months. A total of 187 male patients consulted us with the complaint of
sterility, and the semen of 173 patients was examined, sixty two cases were diagnosed as
azoospermia, 34 as severe
oligozoospermia, 17 as moderate
oligozoospermia and 60 cases as normospermia. Based upon the results of semen examination, endocrinological examination and so on, 78 cases were diagnosed as idiopathic spermatogenetic dysfunction. Serum
follicle stimulating hormone (FSH) levels in
azoospermia patients were significantly higher than those of normal males statistically, and the serum FSH level was considered to correlate with the damage of spermatogenesis. We performed serial treatment using
kallikrein and/or
human chorionic gonadotropin, on 44 patients. Only patient, who was treated with a high dose
kallikrein, succeeded in impregnating his spouse. Four of our patients with
oligozoospermia had received
chemotherapy for
testicular cancer. Recently, with the progress of anticancer
chemotherapy, curative cases have increased gradually. However, because of adverse reaction,
oligozoospermia cases have also increased. Considering the quality of life, the management of the
sterility may be very important.