[Proposal for a new therapeutic strategy in high genital infections].

Abstract

78 cases of acute salpingitis were treated with the association Oflocet-Augmentin in a multicenter study. An accurate clinical and bacteriological evaluation was carried out prior to the treatment and a control laparoscopy was performed in 31 cases. A Chlamydia infection was responsible in 56 p. cent of the cases; only one bacteria was identified in 56 cases and an association of two or three bacteria in 15 cases; in 7 cases, no bacteria was identified. The antibiotic association was effective in 96 p. cent of the cases, with a good clinical and biological tolerance. Three failure were reported: one in an infection secondary to a non identified bacteria, and two in Chlamydia infections where, despite the clinical cure, a positive culture persisted in the abdomen. The association Oflocet-Augmentation is therefore recommended in the treatment of high genital infections.

• Authors: P Verhoest, J Orfila, F Haider, M Vitse, J C Boulanger
• Journal: Revue francaise de gynecologie et d'obstetrique (Rev Fr Gynecol Obstet) Vol. 84 Issue 12 Pg. 933-40 (Dec 1989) ISSN: 0035-290X [Print] France
• Vernacular Title: Proposition d'une nouvelle stratégie thérapeutique dans les infections génitales hautes.
• PMID: 2696066 (Publication Type: Clinical Trial, English Abstract, Journal Article, Multicenter Study)

Chemical References

• Clavulanic Acids
• Amoxicillin-Potassium Clavulanate Combination
• Amoxicillin
• Ofloxacin

Topics

• Adolescent
• Adult
• Amoxicillin (administration & dosage, therapeutic use)
• Amoxicillin-Potassium Clavulanate Combination
• Chlamydia Infections (drug therapy, microbiology, physiopathology)
• Clavulanic Acids (administration & dosage, therapeutic use)
• Drug Therapy, Combination (administration & dosage, therapeutic use)
• Female
• Humans
• Microbial Sensitivity Tests
• Middle Aged
• Multicenter Studies as Topic
• Ofloxacin (administration & dosage, therapeutic use)
• Salpingitis (drug therapy, microbiology, physiopathology)
• Severity of Illness Index