Abstract |
Previous studies have suggested that increased dietary calcium is associated with a decreased occurrence of pregnancy-induced hypertension. In this study 106 young healthy nulliparous women, residing in Quito, Ecuador, were enrolled in a double-blind, randomized, controlled clinical trial. From 24 weeks gestation until delivery they received either 2 g of elemental calcium per day or a placebo. Calcium supplementation was associated with a significantly decreased risk of pregnancy-induced hypertension, with 4.1% developing pregnancy-induced hypertension in the treatment group versus 27.9% in the placebo group. Treatment was associated with a decrease in both systolic and diastolic blood pressure over the course of pregnancy. In addition, there was a small but significant increase in serum ionized calcium levels in the calcium-supplemented group during the treatment period.
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Authors | P López-Jaramillo, M Narváez, R M Weigel, R Yépez |
Journal | British journal of obstetrics and gynaecology
(Br J Obstet Gynaecol)
Vol. 96
Issue 6
Pg. 648-55
(Jun 1989)
ISSN: 0306-5456 [Print] England |
PMID | 2679864
(Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
- Gluconates
- Calcium Gluconate
- Calcium
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Topics |
- Adolescent
- Calcium
(blood)
- Calcium Gluconate
(therapeutic use)
- Double-Blind Method
- Ecuador
- Female
- Gluconates
(therapeutic use)
- Humans
- Hypertension
(prevention & control)
- Parity
- Pregnancy
- Pregnancy Complications, Cardiovascular
(prevention & control)
- Randomized Controlled Trials as Topic
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