Donor Kidney With Renal Cell Carcinoma Successfully Treated With Radiofrequency Ablation: A Case Report.

Abstract

BACKGROUND:

The risk of donor-transmitted cancer is evident.

CASE REPORT:

We report the case of a 69-year-old woman who was transplanted with a kidney from a deceased donor. Four days after transplantation a routine ultrasound scan revealed a 3-cm tumor in the middle-upper pole of the allograft. A biopsy showed the tumor to be papillary renal cell carcinoma. The patient was treated with radiofrequency ablation. This procedure was complicated by the development of a cutaneous fistula and open surgery was done with resection of an area of necrosis in the kidney and of the fistula. The maintenance immunosuppressive regimen was modified with a change in treatment to everolimus in combination with reduced dose mycophenolate and low-dose steroids. The patient was followed for 4.5 years and during that time she remained dialysis independent with an excellent allograft function (serum creatinine, 95 μmol/L [1.04 mg/dL]).

CONCLUSIONS:

To the best of our knowledge, this is the first case in which a donor-transmitted tumor was diagnosed in the renal allograft only 4 days after transplantation and subsequently treated successfully with radiofrequency ablation.

• Authors: S F Christensen, J M Hansen
• Journal: Transplantation proceedings (Transplant Proc) Vol. 47 Issue 10 Pg. 3031-3 (Dec 2015) ISSN: 1873-2623 [Electronic] United States
• PMID: 26707334 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2015 Elsevier Inc. All rights reserved.

Topics

• Aged
• Biopsy
• Carcinoma, Renal Cell (pathology, surgery)
• Catheter Ablation (methods)
• Female
• Humans
• Kidney (pathology, surgery)
• Kidney Neoplasms (pathology, surgery)
• Kidney Transplantation
• Middle Aged
• Tissue Donors
• Transplant Recipients
• Transplantation, Homologous