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One Year Outcomes of Photorefractive Keratectomy with the Application of Mitomycin-C in the Treatment of Mild to Moderate Hyperopia.

AbstractPURPOSE:
To evaluate refractive and visual outcomes of photorefractive keratectomy with mitomycin-C. (PRK-MMC) for the treatment of mild to moderate hyperopia.
MATERIALS AND METHODS:
This case series enrolled 21 patients with up to +5.50 diopters (D) of hyperopia. All 42 eyes were treated with the Concerto (Wavelight) or the Technolas 217-Z (Bausch and Lomb) excimer laser. Outcome measures included best corrected distance vision acuity (BCVA) and uncorrected distance vision correction and refraction at 1, 3, 6, and 12 months postoperatively.
RESULTS:
Mean patient age was 44.8 ± 11.3 years. Preoperatively, mean manifest refractive spherical equivalent (MRSE) was + 2.00 D ± 0.76 D and mean spherical refractive error was + 2.57 D ± 0.87 D (range, +1.25 D to + 5.50 D). At 12 months postoperatively, mean MRSE was + 0.1 D ± 0.61 D. MRSE was within ± 0.50 D of emmetropia in 29 eyes (69%), and 18 eyes (43%) had 20/20 uncorrected distant visual acuity. BCVA increased by two lines or more in three eyes (7.1%) and one line in two eyes (4.7%); 31 eyes showed no change, three eyes (7.1%) lost one line, and three other eyes (7.1%) lost two lines of BCVA. No eyes lost more than two lines of BCVA. Complications included Grade 2 peripheral haze in two eyes which cleared by 12 months postoperatively.
CONCLUSION:
PRK-MMC was a safe and predictable method for the correction of mild to moderate hyperopia.
AuthorsAlireza Habibollahi, Hassan Hashemi, Mohammad Amin Seyedian, Shiva Mehravaran, Soheila Asgari, Sam Habibollahi, Sina Habibollahi, Mehdi Khabazkhoob
JournalMiddle East African journal of ophthalmology (Middle East Afr J Ophthalmol) 2015 Oct-Dec Vol. 22 Issue 4 Pg. 484-8 ISSN: 0975-1599 [Electronic] India
PMID26692722 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Alkylating Agents
  • Mitomycin
Topics
  • Adult
  • Alkylating Agents (administration & dosage)
  • Combined Modality Therapy
  • Female
  • Follow-Up Studies
  • Humans
  • Hyperopia (classification, physiopathology, surgery)
  • Lasers, Excimer (therapeutic use)
  • Male
  • Middle Aged
  • Mitomycin (administration & dosage)
  • Photorefractive Keratectomy (methods)
  • Postoperative Period
  • Prospective Studies
  • Refraction, Ocular
  • Treatment Outcome
  • Vision Tests
  • Visual Acuity (physiology)

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