Abstract | BACKGROUND:
Cholangiocarcinoma is an invasive biliary malignancy with poor prognosis. Diagnostic accuracy of conventional methods is low which is mainly due to the specific anatomy of the disease. The aim of this study was to evaluate the diagnostic value of biochemical profile and tumor marker of the bile in patients with malignant cholestasis compared to that of choledocholithiasis. METHODS: In this cross-sectional study, 46 patients with extrahepatic cholestasis were enrolled (20 patients with malignant cholestasis and 26 patients with choledocolithiasis) A definitive diagnosis of cholangiocarcinoma was made by imaging, cytology and biopsy. Bile fluid was obtained by aspiration through endoscopic retrograde cholagiopantreatography (ERCP) catheter or percutaneous drainage in patients with choledocolithiasis and cholangiocarcinoma respectively. Sex and age were matched in two groups. Data regarding the biochemical profile ( triglyceride, (TG), cholesterol, billirubin and HDL) and CA19.9 level of the bile fluid were collected, then using the SPSS software, the data were analyzed. RESULTS: CONCLUSION:
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Authors | Hassan Taheri, Naser Ghemian, Yaser Taghavi, Javad Shokry-Shirani |
Journal | Caspian journal of internal medicine
(Caspian J Intern Med)
Vol. 6
Issue 3
Pg. 165-9
( 2015)
ISSN: 2008-6164 [Print] Iran |
PMID | 26644885
(Publication Type: Journal Article)
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