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Placental site trophoblastic tumor and choriocarcinoma: an unusual presentation.

AbstractBACKGROUND:
Mixed trophoblastic tumor composed of choriocarcinoma and placental site trophoblastic tumor was diagnosed on histopathology slides review, is a very rare mixed tumor and cured after adjuvant chemotherapy.
CASE PRESENTATION:
Twenty-nine years old, Para 2 female presented with 4 months history of irregular vaginal bleeding after an uncomplicated vaginal delivery. Abdominal examination showed 14 weeks uterus with β-hCG level of 14,889 mIU/ml. Slides review confirmed the diagnosis of placental site trophoblastic tumor (PSTT). Patient underwent total abdominal hysterectomy and resection of anterior vaginal wall mass. Post operative (48 h) β-hCG level was 6016 mIU/ml. Final pathology showed mixed trophoblastic tumor composed of choriocarcinoma (CC) and PSTT. Adjuvant chemotherapy started and continued for three cycles after achieving normal β-hCG.
CONCLUSION:
PSTT is a rare disease and potentially curable. Differential diagnosis in women presented with vaginal bleeding and a uterine mass in the post partum period must include gestational trophoblastic disease.
AuthorsAbdulrahim Gari
JournalBMC research notes (BMC Res Notes) Vol. 8 Pg. 703 (Nov 23 2015) ISSN: 1756-0500 [Electronic] England
PMID26597227 (Publication Type: Journal Article)
Topics
  • Adult
  • Choriocarcinoma (diagnosis, surgery)
  • Female
  • Humans
  • Hysterectomy
  • Pregnancy
  • Trophoblastic Tumor, Placental Site (diagnosis, surgery)
  • Uterine Neoplasms (diagnosis, surgery)

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