Immunotherapy for Infectious Diseases: Past, Present, and Future.

Abstract

Passive immunotherapy for established infections, as opposed to active immunization to prevent disease, remains a tiny niche in the world of antimicrobial therapies. Many of the passive immunotherapies currently available are directed against bacterial toxins, such as botulism, or are intended for agents of bioterrorism such as anthrax, which fortunately has remained rare. The emergence of Ebola virus and multi-drug resistant pathogens, however, may breathe new life into the immunotherapy field as researchers seek non-antibiotic interventions for infectious diseases.

• Authors: Akshay Manohar, Jasmine Ahuja, John K Crane
• Journal: Immunological investigations (Immunol Invest) Vol. 44 Issue 8 Pg. 731-7 ( 2015) ISSN: 1532-4311 [Electronic] England
• PMID: 26575462 (Publication Type: Journal Article, Review)

Chemical References

• Antibodies
• Bacterial Toxins
• Cytokines
• Viral Proteins

Topics

• Animals
• Antibodies (metabolism)
• Bacillus anthracis (immunology)
• Bacterial Toxins (immunology)
• Bioterrorism (prevention & control)
• Cytokines (immunology, metabolism)
• Ebolavirus (immunology)
• Humans
• Immunization, Passive
• Infections (immunology, therapy)
• Viral Proteins (immunology)