Duodenal gangliocytic paraganglioma with lymph node metastasis in a 17-year-old boy.

Abstract

A case of duodenal gangliocytic paraganglioma (DGP) in a 17-year-old boy is presented. In this case a lymph node in the peripancreatic region was involved by a metastatic tumor. A review of the literature on DGP indicates that this case represents the youngest patient and is the second case of DGP with metastasis. Immunohistochemical staining for neuron-specific enolase (NSE), neurofilament (NF), pancreatic polypeptide, and somatostatin showed positive results for epithelioid and ganglion-like cells, whereas spindle cells showed immunoreactivities for S-100 protein, NSE, and NF. The histogenesis of DGP is discussed.

• Authors: K Inai, T Kobuke, S Yonehara, S Tokuoka
• Journal: Cancer (Cancer) Vol. 63 Issue 12 Pg. 2540-5 (Jun 15 1989) ISSN: 0008-543X [Print] United States
• PMID: 2655873 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• S100 Proteins
• Pancreatic Polypeptide
• Phosphopyruvate Hydratase

Topics

• Adolescent
• Duodenal Neoplasms (analysis, pathology)
• Humans
• Immunoenzyme Techniques
• Lymphatic Metastasis
• Male
• Neurofibrils (analysis)
• Pancreatic Polypeptide (analysis)
• Paraganglioma (analysis, pathology, secondary)
• Phosphopyruvate Hydratase (analysis)
• S100 Proteins (analysis)