Abstract | BACKGROUND: METHODS: The investigation was conducted as a retrospective cohort study with parallel group design. Three subsamples of trauma patients were compared: no analgesia (n = 275), pentazocine analgesia (n = 888), and ketamine analgesia (n = 713). Physiologic severity scores were calculated based on rated values for respiratory rate, blood pressure, and consciousness. The associations between outcomes and explanatory variables were assessed using a generalized linear model. RESULTS: Paramedic administration of analgesia was associated with a better physiologic severity score (PSS) outcome (p = 0.01). In the two subsamples receiving analgesia significantly better outcomes were observed for respiration (p < 0.0001) and systolic blood pressure (p < 0.0001). In patients with Injury Severity Score >8 ketamine was associated with a significantly better effect on the systolic blood pressure compared to opioid analgesia (p = 0.03). CONCLUSION:
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Authors | Ole Kristian Losvik, Mudhafar Kareem Murad, Eystein Skjerve, Hans Husum |
Journal | Scandinavian journal of trauma, resuscitation and emergency medicine
(Scand J Trauma Resusc Emerg Med)
Vol. 23
Pg. 94
(Nov 09 2015)
ISSN: 1757-7241 [Electronic] England |
PMID | 26552691
(Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Analgesics
- Analgesics, Opioid
- Ketamine
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Topics |
- Adult
- Analgesia
(methods)
- Analgesics
(administration & dosage)
- Analgesics, Opioid
(administration & dosage)
- Cohort Studies
- Emergency Medical Services
(methods)
- Female
- Follow-Up Studies
- Humans
- Iraq
- Ketamine
(administration & dosage)
- Male
- Pain Management
(methods)
- Pain Measurement
- Patient Safety
- Retrospective Studies
- Risk Assessment
- Survival Rate
- Time Factors
- Trauma Severity Indices
- Treatment Outcome
- Wounds and Injuries
(diagnosis, drug therapy, mortality)
- Young Adult
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