Familial Churg-Strauss Syndrome in a Sister and Brother.

Abstract

Churg-Strauss syndrome (CSS) is a granulomatous small vessel vasculitis. It is characterized by asthma, allergic granulomatosis and vasculitis. This syndrome is rare in children. A 5 years old boy was admitted with cough, fever and dyspnea for 2 weeks. On the basis of laboratory data (peripheral eosinophilia), associated with skin biopsy, and history of CSS in his sister, this disease was eventually diagnosed. The patient had good response to corticosteroid. In every asthmatic patient with prolonged fever, eosinophilia and multisystemic involvment, CSS should be considered.

• Authors: Soheyla Alyasin, Maryam Khoshkhui, Reza Amin
• Journal: Iranian journal of allergy, asthma, and immunology (Iran J Allergy Asthma Immunol) Vol. 14 Issue 3 Pg. 338-40 (Jun 2015) ISSN: 1735-1502 [Print] Iran
• PMID: 26546904 (Publication Type: Journal Article)

Topics

• Child, Preschool
• Churg-Strauss Syndrome (drug therapy, genetics, pathology)
• Female
• Humans
• Male
• Pedigree
• Siblings