Abstract |
The authors review all double-blind studies assessing the efficacy of lithium treatment in schizophrenia. They conclude that active affective symptoms, previous affective episodes, and a family history of affective disorder may predict a favorable response to lithium. However, methodological problems in past studies (e.g., small samples, lack of strict diagnostic criteria) suggest that further clinical trials are warranted.
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Authors | N Atre-Vaidya, M A Taylor |
Journal | The Journal of clinical psychiatry
(J Clin Psychiatry)
Vol. 50
Issue 5
Pg. 170-3
(May 1989)
ISSN: 0160-6689 [Print] United States |
PMID | 2654127
(Publication Type: Clinical Trial, Journal Article, Review)
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Chemical References |
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Topics |
- Chronic Disease
- Clinical Trials as Topic
- Double-Blind Method
- Humans
- Lithium
(therapeutic use)
- Mood Disorders
(complications, genetics)
- Probability
- Research Design
(standards)
- Schizophrenia
(complications, drug therapy)
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