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Lidocaine Skin Patch (Lidopat® 5%) Is Effective in the Treatment of Traumatic Rib Fractures: A Prospective Double-Blinded and Vehicle-Controlled Study.

AbstractOBJECTIVE:
The purpose of this study was to determine the efficacy of the Lidopat(®) 5% skin patch in relieving rib fracture pain.
SUBJECTS AND METHODS:
From June 2009 to May 2011, 44 trauma patients with isolated rib fractures were enrolled in this study and randomized in a double-blind method into 2 groups. The experimental group (group E: 27 patients) used a Lidopat(®) 5% skin patch at the trauma site and took an oral analgesic drug for pain relief. The placebo group (group P: 17 patients) used a placebo vehicle patch and an oral analgesic drug.
RESULTS:
The mean age, weight and hospital stay of patients were 56.8 ± 13.8 years, 67.4 ± 12.6 kg and 6.34 ± 1.3 days, respectively. In the first 4 days, there were no significant differences in pain scores between the groups (p > 0.05). After the 5th day, the average pain score was significantly less in group E (mean 1.5) than in group P (mean 3.10; p < 0.05). There was no significant difference in the number of fractured ribs between groups (p = 0.904). The use of meperidine and the length of hospital stay (6.0 vs. 6.9 days) were both significantly less in group E (p = 0.043 and 0.009, respectively).
CONCLUSION:
In this study, the use of the Lidopat(®) 5% skin patch in patients with isolated rib fractures alleviated pain and shortened the hospital stay, and a lower dose of pain-relieving medication was used.
AuthorsYu-Jen Cheng
JournalMedical principles and practice : international journal of the Kuwait University, Health Science Centre (Med Princ Pract) Vol. 25 Issue 1 Pg. 36-9 ( 2016) ISSN: 1423-0151 [Electronic] Switzerland
PMID26539836 (Publication Type: Journal Article, Randomized Controlled Trial)
Copyright© 2015 S. Karger AG, Basel.
Chemical References
  • Analgesics, Opioid
  • Anesthetics, Local
  • Lidocaine
  • Meperidine
Topics
  • Analgesics, Opioid (therapeutic use)
  • Anesthetics, Local (administration & dosage)
  • Double-Blind Method
  • Drug Utilization (statistics & numerical data)
  • Female
  • Humans
  • Length of Stay (statistics & numerical data)
  • Lidocaine (administration & dosage)
  • Male
  • Meperidine (therapeutic use)
  • Middle Aged
  • Pain (drug therapy, etiology)
  • Prospective Studies
  • Rib Fractures (complications)
  • Transdermal Patch
  • Visual Analog Scale

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