Abstract | BACKGROUND: METHODS: Single institution retrospective review of all premature, low birth weight infants with NEC from January 2006 to December 2013 was conducted. RESULTS: NEC was identified in 114 premature, low birth weight infants, 59 (51.8%) of which required surgical management. Surgical NEC infants were born younger (25.8 ± 4.0 vs 27.8 ± 3.3 weeks, P = .005) and weighed less at birth (829 ± 281 vs 938 ± 271 g, P = .038) than those managed medically. There was no difference in the use of PN (37.7% vs 31.4%, P = .541) between surgical and medical NEC patients. There was no statistically significant difference in mortality at discharge between patients who had PN at NEC onset and those who did not (31.4% vs 42.6%, P = .294) CONCLUSION: In this single-center study, supplemental PN at NEC onset does not appear to significantly improve outcomes as demonstrated by rates of surgical intervention and in-hospital mortality.
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Authors | Adesola C Akinkuotu, Sushma Nuthakki, Fariha Sheikh, Stephanie M Cruz, Stephen E Welty, Oluyinka O Olutoye |
Journal | American journal of surgery
(Am J Surg)
Vol. 210
Issue 6
Pg. 1045-9; discussion 1049-50
(Dec 2015)
ISSN: 1879-1883 [Electronic] United States |
PMID | 26518162
(Publication Type: Journal Article)
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Copyright | Copyright © 2015 Elsevier Inc. All rights reserved. |
Topics |
- Enterocolitis, Necrotizing
(mortality, therapy)
- Female
- Hospital Mortality
- Humans
- Infant, Low Birth Weight
- Infant, Newborn
- Infant, Premature
- Male
- Parenteral Nutrition
- Retrospective Studies
- Treatment Outcome
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