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Propionibacterium acnes immunotherapy in chronic recurrent canine pyoderma. An adjunct to antibiotic therapy.

Abstract
In a randomized, double-blind, placebo-controlled study, dogs with chronic recurrent pyoderma were treated with antibiotics plus intravenous injections of either Propionibacterium acnes or placebo. Responses (an increase, decrease, or clearing of lesions) were measured and evaluated statistically. Eighty percent (12 of 15) of the dogs treated with antibiotics and P acnes compared with 38% (five of 13) of the dogs treated with antibiotics and placebo responded with significant improvement or complete remission of lesions at the end of the 12-week treatment schedule (P less than 0.05).
AuthorsA M Becker, T A Janik, E K Smith, C A Sousa, B A Peters
JournalJournal of veterinary internal medicine (J Vet Intern Med) 1989 Jan-Mar Vol. 3 Issue 1 Pg. 26-30 ISSN: 0891-6640 [Print] United States
PMID2647969 (Publication Type: Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Anti-Bacterial Agents
Topics
  • Animals
  • Anti-Bacterial Agents (therapeutic use)
  • Clinical Trials as Topic
  • Combined Modality Therapy
  • Dog Diseases (therapy)
  • Dogs
  • Double-Blind Method
  • Female
  • Immunotherapy (veterinary)
  • Male
  • Propionibacterium acnes (immunology)
  • Pyoderma (therapy, veterinary)
  • Random Allocation
  • Recurrence

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