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Edema disease-like brain lesions in gnotobiotic piglets infected with Escherichia coli serotype O157:H7.

Abstract
Gnotobiotic piglets inoculated with Escherichia coli serotype O157:H7 strains that produced Shiga-like toxin II developed brain lesions similar to those observed in edema disease of swine, including arteriolar necrosis and malacia. Loss of ability to produce Shiga-like toxin II resulted in loss of ability to cause brain lesions.
AuthorsD H Francis, R A Moxley, C Y Andraos
JournalInfection and immunity (Infect Immun) Vol. 57 Issue 4 Pg. 1339-42 (Apr 1989) ISSN: 0019-9567 [Print] United States
PMID2647636 (Publication Type: Journal Article)
Topics
  • Animals
  • Brain Edema (microbiology, pathology, veterinary)
  • Edema Disease of Swine (microbiology, pathology)
  • Escherichia coli (classification, pathogenicity)
  • Escherichia coli Infections (microbiology, pathology, veterinary)
  • Germ-Free Life
  • Swine
  • Virulence

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